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 Indian J Med Microbiol  
 

Figure 6: Histopathological changes in the oral mucosa of rats at different observation periods during induction of OSMF: 6a - Normal oral mucosa; 6b - 1 month induction: no change in the thickness of the epithelial lining (a), no significant alteration of collagen content in submucosa (b); 6c - 2 months induction: slight thinning of epithelial lining (a), moderately increased collagen content in submucosa (b); 6d - 4 months induction: very thin epithelial lining (a), white patch in the mucosa and thick collagen deposition in submucosa (b)

Figure 6: Histopathological changes in the oral mucosa of rats at different observation periods during induction of OSMF: 6a - Normal oral mucosa; 6b - 1 month induction: no change in the thickness of the epithelial lining (a), no significant alteration of collagen content in submucosa (b); 6c - 2 months induction: slight thinning of epithelial lining (a), moderately increased collagen content in submucosa (b); 6d - 4 months induction: very thin epithelial lining (a), white patch in the mucosa and thick collagen deposition in submucosa (b)