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 Indian J Med Microbiol  
 

Figure 5: Immunohistochemistry was conducted and we found six chondro-ossification angiogenic and inflammatory biomarkers. (a) TGF-B1. (b) IHH in combination with TGF-B1 or BMP2. (c) BMP-2 overexpression in combination with or without IHH, promoting expression of osteogenic markers osteopontin and osteocalcin. (d) CD34 suggest to induce endothelial cells barrier destabilisation that may accompany sprout as well as tube formation. (e) and (f) OCN and OPN markers for bone formation process

Figure 5: Immunohistochemistry was conducted and we found six chondro-ossification angiogenic and inflammatory biomarkers. (a) TGF-B1. (b) IHH in combination with TGF-B1 or BMP2. (c) BMP-2 overexpression in combination with or without IHH, promoting expression of osteogenic markers osteopontin and osteocalcin. (d) CD34 suggest to induce endothelial cells barrier destabilisation that may accompany sprout as well as tube formation. (e) and (f) OCN and OPN markers for bone formation process