Indian Journal of Dental Research

ORIGINAL RESEARCH
Year
: 2020  |  Volume : 31  |  Issue : 6  |  Page : 872--876

Protective role of neutrophils in periodontal inflammation


Rajapriya Perumalsamy1, Jaideep Mahendra1, Little Mahendra2, Meenakshi Sethuraman3, Kavyasri3, V Madhusudhan Rao4 
1 Department of Periodontology, Meenakshi Academy of Higher Education and Research, Faculty of Dentistry, Meenakshi Ammal Dental College and Hospital, Dubai, UAE
2 Maktoum Bin Hamdan Dental University College, Dubai, UAE
3 Department of Dentistry, Meenak Academy of Higher Education and Research, Faculty of Dentistry, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu, India
4 Department of Physiology, Meenakshi Academy of Higher Education and Research, Faculty of Dentistry, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Jaideep Mahendra
Department of Periodontics, Meenakshi Academy of Higher Education and Research, Faculty of Dentistry, Meenakshi Ammal Dental College and Hospital, Alapakkam Road, Maduravoyal, Chennai - 600 095, Tamil Nadu
UAE

Aim: The quantification of neutrophils in blood is done to primarily screen the patients with acute infections. On the other hand, the neutrophils have also shown the antimicrobial activity by allowing the host cells to perform the primary function of preventing the wounds from being infected. The aim of this study was to quantify the blood neutrophil count in patients with chronic gingivitis and chronic periodontitis and to compare with the healthy controls in order to assess the protective role of neutrophils in periodontal inflammation. Methods and Material: A total of 30 subjects in the age group of 30–55 years were selected. Based on the clinical examination, the subjects were divided into three groups Group I (healthy), Group II (chronic gingivitis) and Group III (chronic periodontitis). The clinical parameters such as modified gingival index (MGI) and clinical attachment level (CAL) were recorded. Two millilitres of venous blood was collected from each participant in all the groups and the differential neutrophil counts were obtained using the Neubauer's chamber under a light microscope. One way ANOVA test was used to calculate the mean and standard deviation for MGI, CAL and blood neutrophil count among various groups. Results: The mean neutrophil counts in the various study groups were 63.300, 64.100 and 60.800 in Group I, Group II and Group III, respectively. Though there was a decrease in the mean neutrophil count from Group II to Group III, there was no statistically significant difference between the groups. Conclusion: In our study, there was no significant increase in neutrophil count in chronic periodontitis as compared to healthy controls, thereby explaining the protective role of neutrophils in periodontal inflammation.


How to cite this article:
Perumalsamy R, Mahendra J, Mahendra L, Sethuraman M, Kavyasri, Rao V M. Protective role of neutrophils in periodontal inflammation.Indian J Dent Res 2020;31:872-876


How to cite this URL:
Perumalsamy R, Mahendra J, Mahendra L, Sethuraman M, Kavyasri, Rao V M. Protective role of neutrophils in periodontal inflammation. Indian J Dent Res [serial online] 2020 [cited 2021 May 12 ];31:872-876
Available from: https://www.ijdr.in/article.asp?issn=0970-9290;year=2020;volume=31;issue=6;spage=872;epage=876;aulast=Perumalsamy;type=0