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SYSTEMATIC REVIEW Table of Contents   
Year : 2020  |  Volume : 31  |  Issue : 5  |  Page : 774-781
Post-operative pain after using sodium hypochlorite and chlorhexidine as irrigation solutions in endodontics: Systematic review and meta-analysis of randomised clinical trials


1 Dental School of Presidente Prudente, University of Western Sao Paulo, Presidente Prudente, SP; Graduate Program in Dentistry, University of Western Sao Paulo, Presidente Prudente, SP, Brazil
2 Graduate Program in Dentistry, University of Western Sao Paulo, Presidente Prudente, SP, Brazil
3 Dental School of Presidente Prudente, University of Western Sao Paulo, Presidente Prudente, SP, Brazil

Correspondence Address:
Dr. Graziela G Mori
Rua José Bongiovani, 700 - Cidade Universitária - Presidente Prudente, SP
Brazil
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijdr.IJDR_294_19

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Context: Is it possible that the irrigating solutions can have the potential to cause post-operative pain? Unfortunately, the current literature does not provide clear guidance. Aim: The purpose of this systematic review and meta-analysis was to comprehensively review two different irrigation solutions (sodium hypochlorite and chlorhexidine) regarding the post-operative pain after endodontic treatment. Settings and Design: This study was prepared according to the Cochrane criteria for creating a systematic review and meta-analysis and confirms the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Material and Methods: This search was conducted in the PubMed/MEDLINE, SCOPUS and Cochrane Library databases until February 2018 to answer the In [(Population) what is the effect of (Intervention) on (Outcome), compared with (Comparison) Intervention] (PICO) question: could sodium hypochlorite cause more post-operative pain than chlorhexidine in teeth subjected to endodontic treatment? The primary outcome was overall post-operative pain after 24 h. Results: After applying the inclusion and exclusion criteria, three randomized clinical trials fulfilled the eligibility criteria, and two were subjected to the meta-analysis. There was no difference in post-operative pain between the tested irrigating solutions. Conclusions: There are few studies published in the current literature; therefore, additional randomized clinical studies are required to on this topic to help clinicians make the best decision concerning treatment.


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