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ORIGINAL RESEARCH Table of Contents   
Year : 2012  |  Volume : 23  |  Issue : 5  |  Page : 628-632
Comparison of some salivary characteristics between children with and without early childhood caries

1 Department of Pediatric Dentistry, Dental School, Rafsanjan University of Medical Sciences, Rafsanjan, Kerman, Iran
2 Department of Biochemistry and Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran

Correspondence Address:
Ali Bagherian
Department of Pediatric Dentistry, Dental School, Rafsanjan University of Medical Sciences, Rafsanjan, Kerman
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-9290.107380

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Background and Aim: Early childhood caries (ECC) is one of the most common chronic childhood diseases. Saliva as a host factor plays an essential role in maintaining the integrity of oral structures. The aim of the present study was to compare resting salivary pH, buffering capacity, and secretory immunoglobulin A (sIgA), calcium, and phosphate concentrations between children with and without ECC. Materials and Methods: In this cross-sectional study, samples of unstimulated saliva of 90 children (45 in ECC group and 45 in caries-free group) were taken with Scully method. The pH and buffering capacity were determined by pH meter. sIgA, calcium, and phosphate concentrations were quantitated with ELISA, CPC photometric, and phosphomolybdate/UV methods. Results: The mean resting salivary pH was significantly higher among children without ECC and the buffering capacity was significantly better among this group (P = 0.002). The mean sIgA concentration was significantly higher among the ECC group (P = 0.015). There were no statistically significant differences between calcium and phosphate concentrations between the two groups. Conclusion: The higher mean resting salivary pH and better buffering capacity found in children without ECC are probably the contributing factors that protect against caries development; but further studies are needed to understand the effects of saliva and its characteristics and components on ECC.

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