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 Indian J Med Microbiol  
 

Figure 3: An increase in innervation in the areas of prominent subepithelial lymphocytic infiltration in reticular type of oral lichen planus (OLP-R) and in erosive type of oral lichen planus (OLP-E). H and E staining of OLP-R, OLP-E and noninflamed oral mucosa show in a, c and e, respectively. Avidin-biotin peroxidase complex (abc) staining of PGP 9.5 amplified with glucose oxidase-nickel ammonium sulfated methods from adjacent tissue sections of H and E sections from OLP-R (a), OLP-E (c) and noninflamed oral mucosa: OM (e) presented in b, d and f, respectively. Both PGP9.5-positive nerve fibers (arrows) and lymphocytic infiltration areas (asterisks) are concentrated in the subepithelial areas, in both types of OLP lesions. However, there is no subepithelial innervation with any inflammatory infiltration in noninflamed oral mucosa (e and f). Magnification ×200

Figure 3: An increase in innervation in the areas of prominent subepithelial lymphocytic infiltration in reticular type of oral lichen planus (OLP-R) and in erosive type of oral lichen planus (OLP-E). H and E staining of OLP-R, OLP-E and noninflamed oral mucosa show in a, c and e, respectively. Avidin-biotin peroxidase complex (abc) staining of PGP 9.5 amplified with glucose oxidase-nickel ammonium sulfated methods from adjacent tissue sections of H and E sections from OLP-R (a), OLP-E (c) and noninflamed oral mucosa: OM (e) presented in b, d and f, respectively. Both PGP9.5-positive nerve fibers (arrows) and lymphocytic infiltration areas (asterisks) are concentrated in the subepithelial areas, in both types of OLP lesions. However, there is no subepithelial innervation with any inflammatory infiltration in noninflamed oral mucosa (e and f). Magnification ×200