Indian Journal of Dental Research

LETTER TO EDITOR
Year
: 2016  |  Volume : 27  |  Issue : 1  |  Page : 109-

Author's Reply


M Indira, P Chandrashekar, Kiran Kumar Kattappagari, Lalith Prakash K Chandra, Ravi Teja Chitturi, BV Ramana Reddy 
 Department of Oral Pathology and Microbiology, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India

Correspondence Address:
M Indira
Department of Oral Pathology and Microbiology, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh
India




How to cite this article:
Indira M, Chandrashekar P, Kattappagari KK, Chandra LK, Chitturi RT, Ramana Reddy B V. Author's Reply .Indian J Dent Res 2016;27:109-109


How to cite this URL:
Indira M, Chandrashekar P, Kattappagari KK, Chandra LK, Chitturi RT, Ramana Reddy B V. Author's Reply . Indian J Dent Res [serial online] 2016 [cited 2019 Nov 13 ];27:109-109
Available from: http://www.ijdr.in/text.asp?2016/27/1/109/179843


Full Text

Sir,

This letter is in response to the letter to editor, "Salivary glucose estimation in Type 2 diabetes mellitus patients." First, I would like to thank the author for his critical review and suggestions made. The author has raised queries regarding the time of blood and saliva collection, method of storage of saliva, and usage of equipment for analysis. In our study, blood and salivary samples were collected simultaneously. Saliva sample was collected after instructing the patient to wash his mouth with water. The analyses were done in our hematology department laboratory immediately after collection of the sample. Hence, I have not used any storage method. Since ultraviolet spectrometry is not available in all the laboratories, routinely used semi-automatic analyzer which is cost-effective was used for the study. Only newly diagnosed cases not under any medication including antidiabetics were considered for the study. The suggestion made by the author to include patients on antidiabetics will be considered in further study. The author has mentioned salivary sample collection is ideally recommended when the patient is in fasting state. Here, I have taken samples randomly. There are studies which showed positive correlation between blood and salivary glucose levels when collected randomly. [1] No correlation was observed in studies done by Forbat et al. in 1981, Carda et al. in 2006, and Jurysta et al. in 2009. [2][3][4] As this is a preliminary study with small sample size, studies with large sample size and other parameters should be considered for further validation.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

References

1Sashikumar R, Kannan R. Salivary glucose levels and oral candidal carriage in type II diabetics. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;109:706-11.
2Forbat LN, Collins RE, Maskell GK, Sönksen PH. Glucose concentrations in parotid fluid and venous blood of patients attending a diabetic clinic. J R Soc Med 1981;74:725-8.
3Carda C, Mosquera-Lloreda N, Salom L, Gomez de Ferraris ME, Peydró A. Structural and functional salivary disorders in type 2 diabetic patients. Med Oral Patol Oral Cir Bucal 2006;11:E309-14.
4Jurysta C, Bulur N, Oguzhan B, Satman I, Yilmaz TM, Malaisse WJ, et al. Salivary glucose concentration and excretion in normal and diabetic subjects. J Biomed Biotechnol 2009;2009:430426.