Indian Journal of Dental Research

REVIEW ARTICLE
Year
: 2011  |  Volume : 22  |  Issue : 3  |  Page : 454--461

Orofacial manifestations of hematological disorders: Anemia and hemostatic disorders


Titilope A Adeyemo, Wasiu L Adeyemo, Adewumi Adediran, Abd Jaleel A Akinbami, Alani S Akanmu 
 Departments of Haematology and Blood Transfusion and Oral and Maxillofacial Surgery, College of Medicine, University of Lagos, Nigeria

Correspondence Address:
Titilope A Adeyemo
Departments of Haematology and Blood Transfusion and Oral and Maxillofacial Surgery, College of Medicine, University of Lagos
Nigeria

The aim of this paper is to review the literature and identify orofacial manifestations of hematological diseases, with particular reference to anemias and disorders of hemostasis. A computerized literature search using MEDLINE was conducted for published articles on orofacial manifestations of hematological diseases, with emphasis on anemia. Mesh phrases used in the search were: oral diseases AND anaemia; orofacial diseases AND anaemia; orofacial lesions AND anaemia; orofacial manifestations AND disorders of haemostasis. The Boolean operator «DQ»AND«DQ» was used to combine and narrow the searches. Anemic disorders associated with orofacial signs and symptoms include iron deficiency anemia, Plummer-Vinson syndrome, megaloblastic anemia, sickle cell anemia, thalassaemia and aplastic anemia. The manifestations include conjunctiva and facial pallor, atrophic glossitis, angular stomatitis, dysphagia, magenta tongue, midfacial overgrowth, osteoclerosis, osteomyelitis and paraesthesia/anesthesia of the mental nerve. Orofacial petechiae, conjunctivae hemorrhage, nose-bleeding, spontaneous and post-traumatic gingival hemorrhage and prolonged post-extraction bleeding are common orofacial manifestations of inherited hemostatic disorders such as von Willebrand«SQ»s disease and hemophilia. A wide array of anemic and hemostatic disorders encountered in internal medicine has manifestations in the oral cavity and the facial region. Most of these manifestations are non-specific, but should alert the hematologist and the dental surgeon to the possibilities of a concurrent disease of hemopoiesis or hemostasis or a latent one that may subsequently manifest itself.


How to cite this article:
Adeyemo TA, Adeyemo WL, Adediran A, Akinbami AA, Akanmu AS. Orofacial manifestations of hematological disorders: Anemia and hemostatic disorders.Indian J Dent Res 2011;22:454-461


How to cite this URL:
Adeyemo TA, Adeyemo WL, Adediran A, Akinbami AA, Akanmu AS. Orofacial manifestations of hematological disorders: Anemia and hemostatic disorders. Indian J Dent Res [serial online] 2011 [cited 2014 Apr 17 ];22:454-461
Available from: http://www.ijdr.in/article.asp?issn=0970-9290;year=2011;volume=22;issue=3;spage=454;epage=461;aulast=Adeyemo;type=0