Indian Journal of Dental ResearchIndian Journal of Dental ResearchIndian Journal of Dental Research
HOME | ABOUT US | EDITORIAL BOARD | AHEAD OF PRINT | CURRENT ISSUE | ARCHIVES | INSTRUCTIONS | SUBSCRIBE | ADVERTISE | CONTACT
Indian Journal of Dental Research   Login   |  Users online: 354

Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size         

 


 
CASE REPORT Table of Contents   
Year : 2019  |  Volume : 30  |  Issue : 4  |  Page : 634-638
Traumatic myositis chondro-ossificans of masseter muscle associated with TGF-β1, Indian Hegdehog, BMP2, osteopontin and osteocalcin upregulation: Case report


1 Professor of School of Health Science, Department of Dentistry, Positivo University, Curitiba, Brazil
2 Masters Student at School of Health Science, Department of Dentistry, Positivo University, Curitiba, Brazil
3 Oral and Maxillofacial Resident at Positivo University, Curitiba, Brazil
4 Oral and Maxillofacial Resident at Federal University of Parana, Curitiba, Brazil
5 PhD Student at School of Health Science, Department of Dentistry, Positivo University, Curitiba, Brazil
6 Professor of School of Health Science, Department of Anatomy, Federal University of Parana, Curitiba, Brazil
7 Professor of School of Health Science, Department of Dentistry, Positivo University; Professor of School of Health Science, Department of Stomatology, Federal University of Parana, Curitiba, Brazil

Correspondence Address:
Prof. Rafaela Scariot
Department of Oral and Maxillo-Facial Surgery, Positivo University, Professor Pedro Viriato Parigot de Souza Street, 5300, Curitiba - 81280-330
Brazil
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijdr.IJDR_627_17

Rights and Permissions

Masseter traumatic myositis chondro-ossificans (TMCO) is a rare pathological condition that causes severe mandibular function restriction. The aim of the present study is to report a TMCO case after direct masseter muscle injury and correlate it to bone and cartilage biomarkers up-regulation. Caucasian male patient, 38 years old, seeks treatment nine days after trauma with severe mouth opening limitation. Physical examination revealed a circumscribed hardened area connected to masseter muscle on the left side. Cone beam tomography and ultrasonography of masseter region were requested. There was incomplete fracture between the posterior board of inferior jaw and coronoid process as well as calcification within masseter muscle. The proposed treatment was excisional biopsy of calcification, coronoid process removal to enhance mouth opening as well as incomplete condyle fracture monitoring. Material removed was sent for histological analysis in order to confirm diagnosis. Immuhistochemistry was conducted and it was found that chondro-ossification biomarkers such as TGF-b1, Indian Hegdehog (IHH), BMP2, osteopontin (OP) and osteocalcin (OC) were up-regulated. One-year follow-up showed that the patient is stable with increased mouth opening and satisfactory jaw movements. Pathologists and maxillofacial surgeons must be aware of differential diagnosis of TMCO. Understanding cellular mechanisms of muscle tissue after trauma is also important once cellular pathway modifications leads to clinical features that differ from previously described in literature.


[FULL TEXT] [PDF]*
Print this article     Email this article

 
 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
  Citation Manager
 Access Statistics
  Reader Comments
  Email Alert *
  Add to My List *
 
 

 Article Access Statistics
    Viewed401    
    Printed0    
    Emailed0    
    PDF Downloaded9    
    Comments [Add]    

Recommend this journal