Indian Journal of Dental ResearchIndian Journal of Dental ResearchIndian Journal of Dental Research
HOME | ABOUT US | EDITORIAL BOARD | AHEAD OF PRINT | CURRENT ISSUE | ARCHIVES | INSTRUCTIONS | SUBSCRIBE | ADVERTISE | CONTACT
Indian Journal of Dental Research   Login   |  Users online: 1944

Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size         

 


 
CASE REPORT Table of Contents   
Year : 2013  |  Volume : 24  |  Issue : 6  |  Page : 753-755
Central odontogenic fibroma: Report of case with immunohistochemical study


1 Department of Oral and Maxillofacial Surgery, Dental School, University of Thessaloniki, Thessaloniki, Greece
2 Department of Oral Medicine and Oral Pathology, Dental School, University of Thessaloniki, Thessaloniki, Greece

Correspondence Address:
Athanasios Poulopoulos
Department of Oral Medicine and Oral Pathology, Dental School, University of Thessaloniki, Thessaloniki
Greece
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-9290.127627

Rights and Permissions

Objectives: To report a case of central odontogenic fibroma (COF) with immunohistochemical study. Clinical Presentation: We describe a case of epithelium-rich type of COF in the posterior region of the mandible of a 39-year-old woman. Immunohistochemical examination showed the odontogenic epithelium to be positive for high-molecular-weight cytokeratins, vimentin and CD99, and negative for CAM5.2. The stroma contained some myofibroblasts and many fibroblast-like cells positive for CD99. Conclusion: Our immunohistochemical findings, and especially the positive expression of vimentin from the epithelial cells of COF suggests that these cells are primordial. Last but not least, the presence of a relative small number of myofibroblasts in the stroma justifies the non-aggressive behavior of the neoplasm and supports that a part of stromal collagen of COF is produced by these cells.


[FULL TEXT] [PDF]*
Print this article     Email this article

 
 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
  Citation Manager
 Access Statistics
  Reader Comments
  Email Alert *
  Add to My List *
 
 

 Article Access Statistics
    Viewed2167    
    Printed20    
    Emailed1    
    PDF Downloaded120    
    Comments [Add]    

Recommend this journal