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ORIGINAL RESEARCH Table of Contents   
Year : 2013  |  Volume : 24  |  Issue : 5  |  Page : 533-536
Effect of Lippia sidoides in mouthrinses on de novo plaque formation: A double-blind clinical study in humans


1 Departments of Periodontology, School of Dentistry, University of Fortaleza, UNIFOR, Fortaleza, CE, Brazil
2 Department of Organic Chemistry, School of Pharmacology, University of Fortaleza, UNIFOR, Fortaleza, CE, Brazil

Correspondence Address:
Sérgio Luís da Silva Pereira
Departments of Periodontology, School of Dentistry, University of Fortaleza, UNIFOR, Fortaleza, CE
Brazil
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-9290.123360

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Aim: The aim of this study was to evaluate the antiplaque effect of Lippia sidoides (LS) by in vivo investigation. Materials and Methods: Ten healthy volunteers participated in a cross-over, double-blind clinical study, using a 3-day partial-mouth plaque accumulation model. The participants abolished any method of mechanical oral hygiene and they were randomly assigned initially to use just the following mouth rinses: Distilled water (negative control group), 0.12% chlorhexidine digluconate (positive control group) or 10% LS (test group). The plaque index was recorded in the six anterior upper teeth at the end of the trial and the one-way ANOVA and Bonferroni tests were used to estimate the difference among groups. Results: The clinical results did show statistically significant difference among three groups (P < 0.05), favoring the positive control group and test group, however, no difference in efficacy was found between them (P > 0.05). Conclusions: The mouth rinses containing 0.12% chlorhexidine digluconate and 10% LS were equally able to inhibit plaque re-growth.


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