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Table of Contents   
LETTER TO EDITOR  
Year : 2012  |  Volume : 23  |  Issue : 3  |  Page : 431
Recurrent chronic suppurative osteomyelitis of the mandible and human immunodeficiency virus infection


1 Department of Pediatrics, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India
2 Department of Oral Pathology and Microbiology, Bharati Vidyapeeth University Dental College and Hospital, Navi Mumbai, India
3 Department of Obstetrics and Gynaecology, Jaya Jagadguru Murugharajendra Medical College, Davangere, Karnataka, India
4 Department of Physiology, Mahatma Gandhi Mission Medical College and Hospital, Aurangabad, India
5 Department of Forensic Medicine and Toxicology, Mahatma Gandhi Mission Medical College and Hospital, Aurangabad, India

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Date of Web Publication11-Oct-2012
 

How to cite this article:
Zaki SA, Taqi SA, Nilofer AR, Sami LB, Sami SA. Recurrent chronic suppurative osteomyelitis of the mandible and human immunodeficiency virus infection. Indian J Dent Res 2012;23:431

How to cite this URL:
Zaki SA, Taqi SA, Nilofer AR, Sami LB, Sami SA. Recurrent chronic suppurative osteomyelitis of the mandible and human immunodeficiency virus infection. Indian J Dent Res [serial online] 2012 [cited 2020 Jul 10];23:431. Available from: http://www.ijdr.in/text.asp?2012/23/3/431/102249
Sir,

We read with interest the case report "Recurrent chronic suppurative osteomyelitis of the mandible" by Rajkumar et al. [1] and have the following comments to offer.

Human immunodeficiency virus (HIV) testing was not done in the case described by the authors. The World Health Organization (WHO) estimated that > 39 million persons worldwide were living with HIV infection at the end of 2004. [2] More than 90% of HIV-infected individuals live in developing countries. The sub-Saharan region accounts for the fastest growing HIV-epidemic with India dominating the epidemic in Southeast Asia. HIV-infected patients have defective B cell, monocyte/macrophage, and neutrophil function making them prone for recurrent and serious bacterial infection. [2] The WHO clinical staging of HIV/AIDS is used in many countries to determine eligibility for antiretroviral therapy, particularly in settings in which CD4 testing is not available. In adults and children, the presence of serious and recurrent bone infections puts a HIV-positive patient in stage 3 and stage 4, respectively. Patients with clinical stage 3 or 4 are candidates for starting antiretroviral therapy. [3] Early diagnosis and initiation of antiretroviral therapy provide benefits in terms of higher survival rates in HIV-infected patients. [4]

Through this letter, I would like to re-emphasize our readers that HIV infection should be suspected in cases of chronic and recurrent bone infections.

 
   References Top

1.Rajkumar GC, Hemalatha M, Shashikala R, Kumar DV. Recurrent chronic suppurative osteomyelitis of the mandible. Indian J Dent Res 2010;21:606-8.  Back to cited text no. 1
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2.Yogev R, Chadwick EG. Acquired Immunodeficiency syndrome (Human Immunodeficinecy Virus). In: Behrman RE, Kliegman RM, Jenson HB, Stanton FB editors. Nelson Textbook of Pediatrics, 18 th ed. Philadelphia: WB Saunders; 2008. p. 1427-43.  Back to cited text no. 2
    
3.World Health Organization. WHO Case Definitions of HIV for Surveillance and Revised Clinical Staging and Immunological Classification of HIV-Related Disease In Adults and Children. 2007. Available from http://www. who. int/hiv/pub/ guidelines/ HIVstaging 150307. pdf. [last accessed on February 19, 2011].  Back to cited text no. 3
    
4.Kitahata MM, Gange SJ, Abraham AG, Merriman B, Saag MS, Justice AC, et al. Effect of early versus deferred antiretroviral therapy for HIV on survival. N Engl J Med 2009;360:1815-26.  Back to cited text no. 4
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Correspondence Address:
Syed Ahmed Zaki
Department of Pediatrics, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-9290.102249

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