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REVIEW ARTICLE Table of Contents   
Year : 2010  |  Volume : 21  |  Issue : 4  |  Page : 575-578
Hyaluronic acid: A promising mediator for periodontal regeneration


Department of Periodontics and Oral Implantology, M.M. College of Dental Sciences & Research, M.M.University Mullana, Ambala, Haryana, India

Correspondence Address:
Suresh D Kedige
Department of Periodontics and Oral Implantology, M.M. College of Dental Sciences & Research, M.M.University Mullana, Ambala, Haryana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-9290.74232

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Hyaluronic acid (HA) is a natural-non sulphated high molecular weight glycosaminoglycan that forms a critical component of the extracellular matrix and contributes significantly to tissue hydrodynamics, cell migration and proliferation. The use of HA in the treatment of inflammatory process is established in medical areas such as orthopedics, dermatology and ophthalmology. In the field of dentistry, hyaluronate has shown anti-inflammatory, antiedematous and anti-bacterial effects for the treatment of gingivitis and periodontitis. Due to its potential role in modulation of wound healing, its administration to periodontal wound sites could achieve comparable beneficial effects in periodontal tissue regeneration and periodontal disease treatment.


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