|Year : 2009 | Volume
| Issue : 2 | Page : 190-194
|Association between symptoms of temporomandibular disorders and gender, morphological occlusion, and psychological factors in a group of university students
Leonardo R Bonjardim1, Ricardo J Lopes-Filho2, Guilherme Amado2, Ricardo LC Albuquerque3, Suzane RJ Goncalves2
1 Department of Physiology, Federal University of Sergipe, Aracaju-SE, Brazil
2 Department of Physiology, Tiradentes University, Aracaju-SE, Brazil
3 Department of Physiology, Institute of Technology and Research, Aracaju-SE, Brazil
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|Date of Submission||29-Nov-2006|
|Date of Decision||20-Apr-2007|
|Date of Acceptance||26-Jul-2007|
|Date of Web Publication||23-Jun-2009|
| Abstract|| |
Aim: The purpose of this study was to find out the prevalence of temporomandibular disorder (TMD) in a sample of university students and its relationship to gender, occlusion, and psychological factors.
Materials and Methods: The sample comprised 196 subjects, aged 18-25 years. The TMD degree was evaluated using an anamnestic questionnaire. Morphologic occlusion was evaluated according to Angle classification (classes I, II, and III). The Hospital Anxiety and Depression Scale (HADS), a 14-item self-administered rating scale developed specifically to identify anxiety and depression in nonpsychiatric medical outpatients, was used to assess the levels of anxiety (HADSa) and depression (HADSd).
Statistical Analysis: The incidence of TMD level, malocclusion, anxiety, and depression in both genders was calculated as percentages. Association between TMD degree and occlusion, HADSa, and HADSd was tested using the Chi-square test.
Results: According to our results, 50% of the subjects had TMD, but it was of moderate or severe degree in only 9.18% of them. No statistically significant association could be found between TMD and gender or occlusion. TMD was found to have statistically significant association with HADSa but not with HADSd.
Conclusion : A high prevalence of TMD was found in this student population; however, most of the cases could be classified as mild. Of the variables studied, only HADSa had a statistically significant association with TMD.
Keywords: Anxiety, depression, gender, occlusion, temporomandibular disorder
|How to cite this article:|
Bonjardim LR, Lopes-Filho RJ, Amado G, Albuquerque RL, Goncalves SR. Association between symptoms of temporomandibular disorders and gender, morphological occlusion, and psychological factors in a group of university students. Indian J Dent Res 2009;20:190-4
Temporomandibular disorder (TMD) is a term used to describe a number of related disorders involving the temporomandibular joints (TMJ), masticatory muscles, and occlusion and having some symptoms in common, such as pain, restricted movement, muscle tenderness, and intermittent joint sounds.  Approximately 60-70% of the general population will have at least one of the signs of TMD at some stage in their lives; however, only about 5% actually seek treatment. 
|How to cite this URL:|
Bonjardim LR, Lopes-Filho RJ, Amado G, Albuquerque RL, Goncalves SR. Association between symptoms of temporomandibular disorders and gender, morphological occlusion, and psychological factors in a group of university students. Indian J Dent Res [serial online] 2009 [cited 2013 Jun 20];20:190-4. Available from: http://www.ijdr.in/text.asp?2009/20/2/190/52901
TMD is the most common cause of orofacial pain of non- dental origin.  Its etiology is multifactorial and still poorly understood.  A variety of possible etiological factors have been studied, such as occlusion, ,,,, depression, stress, and anxiety. ,,,,, The importance of psychological factors in the etiology of TMD has usually been emphasized; , they are believed to predispose the individual to chronicity. 
Although TMD may occur at any age, patients most commonly present in early adulthood.  The role of gender in TMD has also been extensively discussed in the literature. TMD is considered to be 1.5-2 times more prevalent in women than in men and 80% of patients treated for this disorder are women.  The gender difference was most prominent in the 20-40 years age-group and was lowest in children, adolescents, and the elderly. 
The purpose of this study was to find out the prevalence of TMD in a sample of university students and its association with gender, morphologic occlusion, and selected psychological factors.
| Materials and Methods|| |
A sample of 196 young adults (101 girls and 95 boys), with age ranging from 18 to 25 years, was randomly selected from among the student population of Tiradentes University, Aracaju-SE, Brazil. The Ethics Committee of Tiradentes University approved the conduct of this research.
The presence and severity of TMD was determined using a self-administered anamnestic questionnaire composed of 10 questions regarding common TMD symptoms. The number and frequency of positive responses were used to categorize the subjects into different groups according to severity of symptoms. The symptoms were transposed into a severity classification according to the number and frequency of positive responses. This questionnaire is a modified version of Helkimo's anamnestic index and has been previously used by Fonseca et al.  and Conti et al.;  it has demonstrated a high efficiency in obtaining a diagnosis and is easy to apply. The scoring system was as follows: A score of '0' indicated the absence of symptoms; a score of '1' was given for a report of an occasional occurrence, a score of '2' was given for each response indicating the presence of dysfunction, and a score of '3' indicated severe pain or bilateral symptoms. (According Conti et al., the score of '3' could only be given for questions 4, 6, and 7 of the anamnestic questionnaire; the questions are given below.)  The sum of the scores was used to group the subjects into four categories as follows: Score 0-3: TMD free; score 4-8: Mild TMD; score 9-14: Moderate TMD; and score 15-23: Severe TMD.
The ten questions in the questionnaire were as follows:
- Do you have difficulty in opening your mouth?
- Do you have difficulty in moving or using your jaw?
- Do you have tenderness or muscular pain when chewing?
- Do you have frequent headaches?
- Do you have neck aches or shoulder pain?
- Do you have pain in or about the ears?
- Are you aware of noises in the jaw joints?
- Do you consider your bite 'normal'?
- Do you use only one side of your mouth when chewing?
- Do you have morning facial pain?
Morphologic occlusion was evaluated according to Angle classification (molar classes I, II, and III).
Hospital anxiety and depression scale
The level of anxiety and depression was self-rated using the Hospital Anxiety and Depression Scale (HADS). HADS consists of seven items for depression (HADSd) and seven items for anxiety (HADSa). The scale was first used in a study by Zigmond and Snaith,  and a Portuguese version has since been validated by Botega et al.  The main characteristic of HADS is that items covering somatic symptoms of anxiety and depression have been eliminated. By defining cutoff values, the HADS subscales give an indication of the severity of the mental disorder: 0-7 = normal; 8-10 = mild; 11-14 = moderate; and 15-21 = severe disorder.  HADS has been extensively tested and has well-established psychometric properties. 
Data were computerized and the SAS package (version 8.2; SAS Institute) was used for analysis. The percentages of subjects with TMD (of different grades of severity), malocclusion, anxiety, and depression in both genders were calculated. Association between TMD degree and occlusion, HADSa, and HADSd was tested using the Chi- square test. The significance level was set at P < 0.05.
| Results|| |
The results obtained from the anamnesis index showed that the percentage of women (57.42%) with some degree of TMD was higher than men (42.11%), but this difference was not statistically significant (P = 0.226).
Only 9.18% of the total sample presented moderate to severe levels of TMD [Table 1]. The majority of the subjects who had moderate or severe levels of TMD exhibited class I occlusion [Table 2]. Moreover, independently of molar class, 49.74% of the total sample had no TMD symptoms according to the questionnaire. No significant association between malocclusion and TMD levels was found (P = 0.112).
The association between TMD levels and anxiety or depression is shown in [Table 3] and [Table 4], respectively. The majority of the participants had no evidence of either anxiety (65.81%) or depression (95.39%) symptoms according to HADS. TMD level was shown to be significantly related to HADSa (P = 0.0001) but not to HADSd (P = 0.0935).
| Discussion|| |
In this study, we evaluated the incidence of TMD in university students and its association with gender, occlusion, and psychological factors. The anamnesis index used to measure TMD degree provided a substantial amount of information in a short period of time and was sensitive and useful for identifying the TMD degree in the studied population. The index proved to be a simple tool that could be easily understood by the volunteers, thus reducing the influence, if any, of the investigator on the individuals and their answers.  The clinically determined prevalence of TMD (which gives the point prevalence) might be lower than that determined by using the questionnaire (which estimates the period prevalence);  for the purposes of this study we have considered only the period prevalence of TMD. Several studies support the validity of the questionnaire for epidemiological studies on TMD symptoms. ,,
In this study, 50% of the subjects had some degree of TMD. This value is a bit lower than that reported by Garcia et al.  (61%) and Conti et al.  (68%), both of whom used the same questionnaire to evaluate TMD in university students. Nassif et al.  found that although the prevalence of TMD in young adults was high, the severity of the condition in this age-group was low. Our study corroborates this, as we found that only 9.18% of the subjects presented moderate or severe degree of TMD and, consequently, needed care and treatment. These data lead us to suggest that TMD evaluation must be discerningly performed in order to identify those who actually could benefit from some intervention.
[Table 1] shows that the percentage of women (57.43%) with TMD is higher than that of men (42.11%); however, this difference was not statistically significant. Other studies have also shown higher prevalence of TMD signs and symptoms in females, ,, with the disorder reported as being 3-6 times more common in women than in men. , Our findings are similar to that reported by Widmalm et al.  and Sonmez et al. 
Several studies have demonstrated that the severity of TMD symptoms varies with the age. The least symptoms are reported by children, adolescents, and the elderly.  In women the symptoms generally increase after puberty, to peak at the reproductive age-group (between 20-40 years). 
In this study, we found no statistically significant association between morphologic occlusion and TMD degree. Our results agree with that of several studies that have also failed to find strong evidence to support of the theory that occlusion plays a role in the etiology of TMD, particularly as the sole cause or the dominant factor. ,,,, Gesch et al.  reported a weak association between malocclusion and the functional and clinical parameters of occlusion as well as subjective TMD. Moreover, no particular morphologic or functional occlusal factor became apparent. Gesch et al. also reported that the occlusal factors that were found were partly protective for TMD, i.e., subjects with these occlusal parameters (i.e., angle class II malocclusion, deep bite, and anterior crossbite) showed fewer signs and symptoms of TMD.
We found a statistically significant association between TMD degree and HADSa [Table 3] but not between TMD degree and HADSd [Table 4]. These outcomes are in agreement with Bonjardim et al.  Mazzetto  asserted that anxiety plays an important role in TMD, acting as a predisposing or aggravating factor. Furthermore, anxiety may be an important factor in the perception of pain, with anxious subjects paying more attention to pain and thereby amplifying the perceived intensity. This possibility has been confirmed by other studies, , which indicate that anxiety is related to increased pain reports in clinical settings.
There is currently considerable evidence that psychological factors are important in TMD, which is the most common cause of chronic facial pain. TMD are often associated with somatic and psychological complaints, including fatigue, sleep disturbances, anxiety, and depression. , Thus, considering that stress is associated with psychological disturbances such as anxiety and depression,  we can say that there appears to be a relationship between stress and degree of TMD in our study.
In conclusion, we found a high prevalence of TMD symptoms in our sample, even though the majority of the cases were classified as being of mild degree. Although a larger percentage of women than men had some symptoms of TMD, the difference was not statistically significant. Morphologic malocclusion (molar class, Angle's classification) was not associated with the presence of TMD symptoms. On the other hand, anxiety (but not depression) was associated with TMD symptoms. The outcomes suggest the importance of recognizing the merits of psychological screening of young adults with a confirmed diagnosis of TMD.
| Acknowledgments|| |
We would like to thank CNPq (Conselho Nacional de Desenvolvimento Cientνfico e Tecnológico, Brazil) for the financial support provided through an institutional studentship.
| References|| |
|1.||Dimitroulis G. Temporomandibular disorders: A clinical update. BMJ 1998;317:190-4. [PUBMED] [FULLTEXT]|
|2.||Macfarlane TV, Gray RJ, Kincey J, Worthington HV. Factors associated with the temporomandibular disorder, pain dysfunction syndrome (PDS): Manchester case-control study. Oral Dis 2001;7:321-30. |
|3.||Irving J, Wood GD, Hackett AF. Does Does temporomandibular disorder pain dysfunction syndrome affect dietary intake? Dent Update 1999;26:405-7. [PUBMED] |
|4.||Egermark-Eriksson I, Ingervall B, Carlsson GE. The dependence of mandibular dysfunction in children on functional and morphologic malocclusion. Am J Orthod 1983;83:187-94. [PUBMED] |
|5.||Lieberman MA, Gazit E, Fuchs C, Lilos P. Mandibular dysfunction in 10- 18 year old school children as related to morphological malocclusion. J Oral Rehabil 1985;12:209-14. [PUBMED] |
|6.||Riolo ML, Brandt D, TenHave TR. Associations between occlusal characteristics and signs and symptoms of TMJ dysfunction in children and young adults. Am J Orthod Dentofacial Orthop 1987;92:467-77. |
|7.||Henrikson T, Ekberg EC, Nilner M. Symptoms and signs of temporomandibular disorders in girls with normal occlusion and Class II malocclusion. Acta Odontol Scand 1997;55:229-35. [PUBMED] |
|8.||De Boever JA, Carlsson GE, Klineberg IJ. Need for occlusal therapy and prosthodontic treatment in the management of temporomandibular disorders: Part I, Occlusal interferences and occlusal adjustment. J Oral Rehabil 2000;27:367-79. [PUBMED] [FULLTEXT]|
|9.||Wexler GB, Steed PA. Psychological factors and temporomandibular outcomes. Cranio 1998;16:72-7. [PUBMED] |
|10.||Yap AU, Tan KB, Hoe JK, Yap RH, Jaffar J. On-line computerized diagnosis of pain-related disability and psychological status of TMD patients: A pilot study. J Oral Rehabil 2001;28:78-87. [PUBMED] [FULLTEXT]|
|11.||Kino K, Sugisaki M, Ishikawa T, Shibuya T, Amagasa T, Miyaoka H. Preliminary psychologic survey of orofacial outpatients: Part 1, Predictors of anxiety or depression. J Orofac Pain 2001;15:235-44. [PUBMED] |
|12.||Sipila K, Veijola J, Jokelainen J, Jarvelin MR, Oikarinen KS, Raustia AM, et al. Association between symptoms of temporomandibular disorders and depression: An epidemiological study of the Northern Finland 1966 Birth Cohort. Cranio 2001;19:183-7. |
|13.||Yap AU, Dworkin SF, Chua EK, List T, Tan KB, Tan HH. Prevalence of temporomandibular disorder subtypes, psychologic distress, and psychosocial dysfunction in Asian patients. J Orofac Pain 2003;17:21-8. [PUBMED] |
|14.||Bonjardim LR, Gaviao MB, Pereira LJ, Castelo PM. Anxiety and depression in adolescents and their relationship with signs and symptoms of temporomandibular disorders. Int J Prosthodont 2005;18:347-52. |
|15.||Kight M, Gatchel RJ, Wesley L. Temporomandibular disorders: Evidence for significant overlap with psychopathology. Health Psychol 1999;18:177-82. [PUBMED] [FULLTEXT]|
|16.||Rollman GB, Gillespie JM. The role of psychosocial factors in temporomandibular disorders. Curr Rev Pain 2000;4:71-81. [PUBMED] |
|17.||Gatchel RJ, Garofalo JP, Ellis E, Holt C. Major psychological disorders in acute and chronic TMD: An initial examination. J Am Dent Assoc 1996;127:1365-70. [PUBMED] [FULLTEXT]|
|18.||Dworkin SF, Huggins KH, LeResche LR, Von Korff M, Howard J, Truelove E, et al. Epidemiology of signs and symptoms in temporomandibular disorders: I, Clinical signs in cases and controls. J Am Dent Assoc 1990;120:273-81. |
|19.||LeResche L. Epidemiology of temporomandibular disorders: Implications for the investigation of etiologic factors. Crit Rev Oral Biol Med 1997;8:291-305. [PUBMED] [FULLTEXT]|
|20.||Meisler JG. Chronic pain conditions in women. J Womens Health 1999;8:313-20. [PUBMED] |
|21.||Fonseca DM. Diagnóstico pela anamnese da disfunηγo craniomandibular. Rev Gaúcha Odont 1994;42:23-8. |
|22.||Conti PC, Ferreira PM, Pegoraro LF, Conti JV, Salvador MC. A cross-sectional study of prevalence and etiology of signs and symptoms of temporomandibular disorders in high school and university students. J Orofac Pain 1996;10:254-62. |
|23.||Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983;67:361-70. |
|24.||Botega NJ, Bio MR, Zomignani MA, Garcia C Jr, Pereira WA. Mood disorders among medical in-patients: A validation study of the hospital anxiety and depression scale HAD. Rev Saude Publica 1995;29:355-63. |
|25.||Mykletun A, Stordal E, Dahl AA. Hospital Anxiety and Depression (HAD) scale: Factor structure, item analyses and internal consistency in a large population. Br J Psychiatry 2001;179:540-4. |
|26.||Conti A, Freitas M, Conti P, Henriques J, Janson G. Relationship between signs and symptoms of temporomandibular disorders and orthodontic treatment: A cross-sectional study. Angle Orthod 2003;73:411-7. |
|27.||Miyake R, Ohkubo R, Takehara J, Morita M. Oral parafunctions and association with symptoms of temporomandibular disorders in Japanese university students. J Oral Rehabil 2004;31:518-23. |
|28.||Nilner M. Relationships between oral parafunctions and functional disturbances and diseases of the stomatognathic system among children aged 7-14 years. Acta Odontol Scand 1983;41:167-72. |
|29.||Matsuka Y, Itoh S, Minakuchi H, Kuboki T, Yamashita A. Validity of questionnaire for epidemiological studies on symptoms of temporomandibular disorders. J Jpn Soc TMJ 1997;9:80-91. |
|30.||Gavish A, Halachmi M, Winocur E, Gazit E. Oral habits and their association with signs and symptoms of temporomandibular disorders in adolescent girls. J Oral Rehabil 2000;27:22-32. |
|31.||Garcia AL, Lacerda NJ, Pereira SLS. Grau de Disfunηγo da ATM e dos movimentos mandibulares em adultos jovens. Rev APCD 1997;51:46. |
|32.||Nassif NJ, Al-Salleeh F, Al-Admawi M. The prevalence and treatment needs of symptomsand signs of temporomandibular disorders among Young adult males. J Oral Rehabil 2003;30:944-50. |
|33.||Barone A, Sbordone L, Ramaglia L. Craniomandibular disorders and orthodontic treatment need in children. J Oral Rehabil 1997;24:2-7. |
|34.||Kapila S, Xie Y. Targeted induction of collagenase and stromelysin by relaxin in unprimed and beta-estradiol-primed diarthrodial joint fibrocartilaginous cells but not in synoviocytes. Lab Invest 1998;78:925-38. |
|35.||Biondi M, Picardi A. Temporomandibular joint pain-dysfunction syndrome and bruxism: Etiopathogenesis and treatment from a psychosomatic integrative viewpoint. Psychother Psychosom 1993;59:84-98. |
|36.||McNeill C. History and evolution of TMD concepts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997;83:51-60. |
|37.||Widmalm SE, Westesson PL, Kim IK, Pereira FJ Jr, Lundh H, Tasaki MM. Temporomandibular joint pathosis related to sex, age, and dentition in autopsy material. Oral Surg Oral Med Oral Pathol 1994;78:416-25. |
|38.||Sonmez H, Sari S, Oksak Oray G, Camdeviren H. Prevalence of temporomandibular dysfunction in Turkish children with mixed and permanent dentition. J Oral Rehabil 2001;2:280-5. |
|39.||Kuttila M, Niemi PM, Kuttila S, Alanen P, Le Bell Y. TMD treatment need in relation to age, gender, stress, and diagnostic subgroup. J Orofac Pain 1998;12:67-74. |
|40.||Liu JK, Tsai, MY. Relationship between morphologic malocclusion and temporomandibular disorders in orthodontic patients prior to treatment. Funct Orthod 1997;14:13-6. |
|41.||Kitai N, Takada K, Yasuda Y, Verdonck A, Carels C. Pain and other cardinal TMJ dysfunction symptoms: A longitudinal survey of Japanese female adolescents. J Oral Rehabil 1997;24:741-8. |
|42.||Watanabe EK, Yatani H, Kuboki T, Matsuka Y, Terada S, Orsini MG et al. The relationship between signs and symptoms of temporomandibular disorders and bilateral occlusal contact patterns during lateral excursions. J Oral Rehabil 1998;25:409-15. |
|43.||Pullinger AG, Seligman DA. Quantification and validation of predictive values of occlusal variables in temporomandibular disorders using a multifactorial analysis. J Prosthet Dent 2000;83:66-75. |
|44.||Gesch D, Bernhardt O, Kirbschus A. Association of malocclusion and functional occlusion with temporomandibular disorders (TMD) in adults: A systematic review of population-based studies. Quintessence Int 2004;35:211-21. |
|45.||Mazzetto MO. Alteraηυes psicossociais em sujeitos com desordens crβnio craniomandibulares. J Bras. Oclusγo, ATM & Dor Orofacial 2001;1:223-43. |
|46.||Marbach JJ, Lennon MC, Dohrenwend BP. Candidate risk factors for temporomandibular pain and dysfunction syndrome: Psychosocial, health behavior, physical illness and injury. Pain 1998;34:139-51. |
|47.||Wahlund K, List T, Ohrbach R. The relationship between somatic and emotional stimuli: A comparison between adolescents with temporomandibular disorders (TMD) and a control group. Eur J Pain 2005;9:219-27. |
|48.||Gameiro GH, da Silva Andrade A, Nouer DF, Ferraz de Arruda Veiga MC. How may stressful experiences caontribute to the development of temporomandibular disorders? Clin Oral Investig 2006;10:261-8. |
Leonardo R Bonjardim
Department of Physiology, Federal University of Sergipe, Aracaju-SE
[Table 1], [Table 2], [Table 3], [Table 4]
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